CAPILLARY ACTION TEST USING PHOTOLUMINESCENT INORGANIC NANOPARTICLES

The invention relates to an in vitro method for the detection and/or quantification of a biological or chemical substance of interest in a liquid sample, by means of a capillary action test, using, as probes, photoluminescent inorganic nanoparticles, of formula A1-xLnxVO4(1-y)(PO4)y (II), in which L...

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Main Authors RICHLY MAXIMILIAN, BOUZIGUES CEDRIC, PREIRA PASCAL, ALEXANDROU ANTIGONI, GACOIN THIERRY
Format Patent
LanguageChinese
English
Published 01.06.2021
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Summary:The invention relates to an in vitro method for the detection and/or quantification of a biological or chemical substance of interest in a liquid sample, by means of a capillary action test, using, as probes, photoluminescent inorganic nanoparticles, of formula A1-xLnxVO4(1-y)(PO4)y (II), in which Ln is selected from europium (Eu), dysprosium (Dy), samarium (Sm), neodymium (Nd), erbium (Er), ytterbium (Yb), thulium (Tm), praseodymium (Pr), holmium (Ho) and the mixtures thereof; A is selected from yttrium (Y), gadolinium (Gd), lanthane (La), lutetium (Lu), and the mixtures thereof; 0 < x < 1; and 0 <= y < 1, said method implementing the detection of luminescence of an emission lifetime shorter than 100 ms of the nanoparticles, after one-photon absorption, by excitation of the matrix at a wavelength which is less than or equal to 320 nm. The invention also relates to a capillary action test comprising the abovementioned nanoparticles as probes, and to the use of such a method for in vitro diagnostic purposes. 本
Bibliography:Application Number: CN201980060683