Biological peptide for treating pulmonary diseases and application of biological peptide

• Main Authors: GU FENGHUA, WANG JIAHUI, LIU NAN, MEI QIBING, XU WENQI, MA SHUMEI, LIU LI, LI LIANG
• Format: Patent
• Language: Chinese; English
• Published: 21.05.2021
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention provides a biological peptide for treating pulmonary diseases and application of the biological peptide. The invention also relates to a preparation method and application of the polypeptide and a pharmaceutical composition containing the polypeptide. The polypeptide has multiple advantages of small molecular weight, low production cost, good water solubility, good stability, long half-life period, small immunogenicity, low toxic and side effects, strong tissue penetrability and the like; and in addition, the biological peptide has remarkable functions of treating and/or relieving the chronic obstructive pulmonary disease and/or preventing, treating and/or relieving asthma. 本发明提供了一种治疗肺疾病的生物肽及其应用。本发明还涉及所述多肽的制法和应用以及含所述多肽的药物组合物。本发明多肽具有多种优点，例如分子量小、生产成本低、水溶性好、稳定性好、半衰期长、免疫原性小、毒副作用低及组织穿透性强等优势；并且，该生物肽具有显著的治疗和/或缓解慢性阻塞性肺疾病和/或预防、治疗和/或缓解哮喘的功能。