Preparation method and application of 4-hydroxy-2-oxo-1-pyrrolidine acetic acid

The invention provides a preparation method of 4-hydroxy-2-oxo-1-pyrrolidine acetic acid, and the preparation method comprises the following steps: mixing oxiracetam and a lithium compound to react, so as to obtain the 4-hydroxy-2-oxo-1-pyrrolidine acetic acid. The preparation method provided by the...

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Bibliographic Details
Main Authors LI YONGCHENG, ZHANG SHAOYU, LIU FAGUANG, LI BIN, ZHANG JIANMING, ZHANG CHENCHEN, WENG QIUJING
Format Patent
LanguageChinese
English
Published 04.05.2021
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The invention provides a preparation method of 4-hydroxy-2-oxo-1-pyrrolidine acetic acid, and the preparation method comprises the following steps: mixing oxiracetam and a lithium compound to react, so as to obtain the 4-hydroxy-2-oxo-1-pyrrolidine acetic acid. The preparation method provided by the invention is simple to operate, high in yield, high in purity and simple and convenient in post-treatment. 本发明提供了一种4-羟基-2-氧代-1-吡咯烷乙酸的制备方法，所述制备方法包括以下步骤：将奥拉西坦与锂化合物混合反应，得到所述4-羟基-2-氧代-1-吡咯烷乙酸。本发明提供的制备方法操作简单，收率高、纯度高，后处理简单方便。
Bibliography:Application Number: CN202011613608