Tetrodotoxin oral preparation, tetrodotoxin freeze-dried tablet and application of tetrodotoxin oral preparation

• Main Authors: XUAN JIANGANG, LI TIANSHAN
• Format: Patent
• Language: Chinese; English
• Published: 27.04.2021
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention discloses a tetrodotoxin oral preparation, a tetrodotoxin freeze-dried tablet and application of the tetrodotoxin oral preparation. The tetrodotoxin oral preparation comprises an active component, a stabilizer and auxiliary additive components, wherein the active component is tetrodotoxin; the stabilizer comprises one or more of lactose, sucrose and glucose; and the auxiliary additive components include pharmaceutically acceptable auxiliary materials or carriers. The tetrodotoxin oral preparation disclosed by the invention can be suitable for various solid tumors and blood tumors, has the characteristics of being convenient to take orally and use, definite in curative effect, slight in side reaction, high in patient compliance and the like, effectively prolongs the lifetime of tumor patients, and improves the life quality of the patients. 本申请公开了一种替曲朵辛口服制剂、替曲朵辛冻干片及其应用，替曲朵辛口服制剂包括活性成分和稳定剂，以及辅助添加成分，所述活性成分为替曲朵辛，所述稳定剂包括乳糖、蔗糖、葡萄糖中的一种或多种，所述辅助添加成分包括药学上可接受的辅料或载体。本发明的替曲朵辛口服制剂可以适用于多种实体瘤和血液肿瘤，具有口服使用方便、疗效确切、副