Ethyl cellulose hollow microcapsule

• Main Authors: JIANG ALI, YU YALAN, MOU CHUANLIN, WANG LINYUAN, DENG HONGBO
• Format: Patent
• Language: Chinese; English
• Published: 16.03.2021
• Subjects: BABY COMFORTERS; CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICALPURPOSES; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; DEVICES FOR RECEIVING SPITTLE; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGINGPHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL ORADMINISTERING FORMS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

The invention discloses a preparation method of an ethyl cellulose hollow microcapsule. The method comprises the following steps of (1) mixing a surfactant, a viscosity additive and deionized water inthe mass ratio of 1:5:100, performing uniform stirring at 60 DEG C, and performing cooling to obtain a water-phase solution; and (2) mixing polyglycerol polyricinoleate with the concentration of 2-9%, ethyecellulose with the concentration of 5-10% and ethyl acetate according to the mass ratio of 4:5:100, and performing uniform stirring at normal temperature to obtain an oil phase solution. According to the invention, a micro-channel outlet is of a conical structure, so that a water-phase solution fluid shears an oil-phase solution fluid to form a monodisperse oil-in-water emulsion, and an oilphase in the oil-in-water emulsion has the characteristic of volatilization, so that an EC microcapsule structure with a hollow structure is prepared; and compared with the prior art, the method hasthe advantages of simplicit