Synthesis method of 2-alkynyl substituted indole compound

• Main Authors: FENG RUOKUN, ZENG FENFEN
• Format: Patent
• Language: Chinese; English
• Published: 12.01.2021
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; METALLURGY; ORGANIC CHEMISTRY

The invention discloses a synthesis method of a 2-alkynyl substituted indole derivative. The synthesis method comprises the following steps: under the actions of a rhodium catalyst, a silver additiveand an oxidant, carrying out cyclization reaction on an aniline derivative and a 1, 3-butadiyne deriv...