Application of lactobacillus plantarum in preparation of composition for relieving chronic inflammation of organism

• Main Authors: CHEN LI'E, REN XUELIANG, CHEN CAILING, CHEN ZUOGUO, SUN SHENG, LI YANJUN, ZHENG ZHIYAO, YU YUNXIA, CHEN SU, YU TENGFEI, ZHOU QINGQING
• Format: Patent
• Language: Chinese; English
• Published: 08.01.2021
• Subjects: DAIRY PRODUCTS, e.g. MILK, BUTTER, CHEESE; FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MAKING THEREOF; MEDICAL OR VETERINARY SCIENCE; MILK OR CHEESE SUBSTITUTES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

The invention relates to the field of microorganisms, and discloses application of lactobacillus plantarum in preparation of a composition for relieving chronic inflammation of an organism. The lactobacillus plantarum is named as 1701, is preserved in China General Microbiological Culture Collection Center on October 23, 2019, has a preservation number of CGMCC No.18728, and is named as lactobacillus plantarum based on classification of microbes. The adopted lactobacillus plantarum can adjust the levels of a cell factor IL-12, an anti-inflammatory factor IL-10 and a proinflammatory factor (including IL-1beta, IL-6, TNF-alpha, MCP-1 and NO) at the same time, so that the lactobacillus plantarum can adapt to chronic inflammation caused by different reasons, and diseases caused by the chronicinflammation can be prevented more comprehensively. 本发明涉及微生物领域，公开了一株植物乳杆菌在制备缓解机体慢性炎症的组合物中的应用。该植物乳杆菌命名为1701，已在2019年10月23日保藏于中国微生物菌种保藏管理委员会普通微生物中心，其保藏编号为CGMCC No.18728，微生物分类命名为植物乳杆菌Lactobacillus plantarum。本发明所采用的植物乳杆菌能同时调节细胞因子I