Preparation method of spaceflight depression syndrome animal model

The invention belongs to the technical field of animal model preparation, and particularly relates to preparation method of a spaceflight depression syndrome animal model. The method comprises the steps of S1, spaceflight depression syndrome model molding, namely adopting closed isolated culture, si...

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Main Authors FAN QUANCHUN, WU XIAORUI, GAO JIANYI, ZHAO SHUANG, WANG JIAPING, LI YONGZHI, LIU YU, LIU JUNLIAN
Format Patent
LanguageChinese
English
Published 05.01.2021
Subjects
AGRICULTURE
ANIMAL HUSBANDRY
CARE OF BIRDS, FISHES, INSECTS
FISHING
FORESTRY
HUMAN NECESSITIES
HUNTING
NEW BREEDS OF ANIMALS
REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR
TRAPPING
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Summary:The invention belongs to the technical field of animal model preparation, and particularly relates to preparation method of a spaceflight depression syndrome animal model. The method comprises the steps of S1, spaceflight depression syndrome model molding, namely adopting closed isolated culture, simulated weightlessness, noise and circadian rhythms to verify the condition of accepting simulated spaceflight stress stimulation of adult SD male rats; and S2, spaceflight depression syndrome model behavioristics evaluation, namely detecting a depression syndrome state condition through a sweet water preference experiment, an open field experiment, a Morris water maze experiment, a step-down experiment and a forced swimming experiment. According to the simulated weightlessness manner, a Chen Jie improved tail crane is adopted, and an angle of 30 degrees is formed between the body and the horizontal plane; for day and night rhythm change, day and night alternation of space flight in 90 minutes in a light and shade
Bibliography:Application Number: CN202010917426