Pyrazolone-fused pyrimidine compound as well as preparation method and application thereof

The invention discloses a pyrazolone-fused pyrimidine compound as well as a preparation method and application thereof. The invention provides a pyrazolone-fused pyrimidine compound as shown in a formula II which is described in the specification. The pyrazolone-fused pyrimidine compound has better...

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Bibliographic Details
Main Authors SHU SIJIE, KE YING, SHI CHEN, XIA GUANGXIN, WANG QIAN, ZHANG ZHIHUI, LIU YANJUN, YU JIANXIN, HUO GUOYONG, ZHANG BINGBIN, MAO YU, GE HUI, LOU JIANGSONG, ZHANG CHI, ZHANG LIN
Format Patent
LanguageChinese
English
Published 29.12.2020
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention discloses a pyrazolone-fused pyrimidine compound as well as a preparation method and application thereof. The invention provides a pyrazolone-fused pyrimidine compound as shown in a formula II which is described in the specification. The pyrazolone-fused pyrimidine compound has better inhibitory activity on WEE1 kinase. 本发明公开了一种吡唑酮并嘧啶类化合物、其制备方法及应用。本发明提供了一种如式II所示的吡唑酮并嘧啶类化合物，该类化合物对WEE1激酶的抑制活性较佳。
Bibliography:Application Number: CN202010601527