COMPLEX HAVING ANTI-HUMAN MUC1 ANTIBODY Fab FRAGMENT, PEPTIDE LINKER AND/OR LIGAND

• Main Authors: AKAIWA MICHINORI, MORINAKA AKIFUMI, YAMADA HIROYOSHI, SANO YORIKATA, SHIRAI HIROKI, HIRAYAMA KAZUNORI, SHIRAISHI NOBUYUKI, ASANO TORU
• Format: Patent
• Language: Chinese; English
• Published: 25.12.2020
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ELECTRIC COMMUNICATION TECHNIQUE; ELECTRICITY; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PICTORIAL COMMUNICATION, e.g. TELEVISION; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

Provided are: a complex having an anti-human MUC1 antibody Fab fragment, a peptide linker and/or a ligand; a diagnostic composition and/or a medicinal composition comprising said complex; and a methodfor diagnosing and/or treating cancer by using said complex. A complex is used in which an anti-human MUC1 antibody Fab fragment is linked to a ligand via a peptide linker or the like. 本发明提供包含抗人MUC1抗体Fab片段、肽接头和/或配体的复合物、包含所述复合物的诊断用组合物和/或药物组合物、以及使用该复合物对癌症进行诊断和/或治疗的方法等。使用借助肽接头等使抗人MUC1抗体Fab片段与配体结合而得到的复合物。