Paracetamol tablet and preparation process thereof

• Main Authors: QIANG ZEMING, XU SANNENG, ZHANG QIANG
• Format: Patent
• Language: Chinese; English
• Published: 15.12.2020
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention discloses a paracetamol tablet and a preparation process thereof, and belongs to the field of paracetamol tablets. The preparation process of the paracetamol tablet comprises the following steps: firstly, preparing raw materials of a medicine; uniformly stirring corn starch and lauryl sodium sulfate, and adding the mixture into boiling water to obtain mixed slurry with the concentration of 16%; putting paracetamol, low-substituted hydroxypropyl cellulose, pregelatinized starch, sucrose and carboxymethyl starch sodium into a mixer, and stirring and mixing the materials; then adding the mixed slurry to prepare a soft medicine material; putting the soft material into a swing type granulator for granulation to prepare medicine granules; drying the medicine granules; and putting lauryl sodium sulfate, magnesium stearate, carboxymethyl starch sodium and lauryl sodium sulfate into the mixer, then adding the medicine granules, and performing secondary mixing in the mixer. 本发明公开了一种对乙酰氨基酚片及其制备工艺，属于对乙酰氨基酚片