Application of radix acanthopanacis senticosi injection to prevention of weightless cardiovascular dysfunction

• Main Authors: FAN QUANCHUN, XU CHONG, GUO LIGUO, WU XIAORUI, GAO JIANYI, ZHAO SHUANG, WANG JIAPING, WANG YUE, WU BIN, LI YONGZHI, LIU YU, LIU JUNLIAN
• Format: Patent
• Language: Chinese; English
• Published: 08.12.2020
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention belongs to the technical field of cardiovascular function prevention, and particularly relates to an application of a radix acanthopanacis senticosi injection to prevention of weightlesscardiovascular dysfunction. Experiments prove that the radix acanthopanacis senticosi injection has a protective effect on cardiovascular dysfunction of a rat simulating weightlessness, and the radixacanthopanacis senticosi injection can increase the stroke volume and the cardiac output and reduce the heart rate by increasing the thickness of the left ventricle of the rat at the final phase of cardiac contraction and diastole, so that the effect of regulating the cardiovascular dysfunction of the rat simulating weightlessness is achieved. The invention proves that the radix acanthopanacis senticosi injection can effectively resist the weightless cardiovascular dysfunction. 本发明属于预防心血管功能技术领域，尤其涉及一种刺五加注射液在预防失重性心血管功能失调中的应用。通过实验证明刺五加注射液对模拟失重大鼠心血管功能失调的具有防护作用，刺五加注射液能够通过增加大鼠心脏收缩和舒张末期左室厚度，提高每搏输出量和心排量，降低心率，从而达到调节模拟失重大鼠心血管功