Microfluidic system for accurately capturing circulating tumor cells and preparation method

• Main Authors: WU FENG, TENG DAOXIANG
• Format: Patent
• Language: Chinese; English
• Published: 01.12.2020
• Subjects: APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; BEER; BIOCHEMISTRY; CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE; CHEMISTRY; ENZYMOLOGY; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PERFORMING OPERATIONS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; SPIRITS; TRANSPORTING; VINEGAR; WINE

The invention discloses a micro-fluidic system for accurately capturing circulating tumor cells and a preparation method, and belongs to the technical field of functional materials, the micro-fluidicsystem comprises a bioimpedance coating and an antibody for functionally modifying the bioimpedance coating, and the antibody is used for specifically recognizing the circulating tumor cells. The micro-fluidic system for accurately capturing the circulating tumor cells is free of toxic and harmful substances in the preparation process, environmentally friendly, simple in technological operation, good in system stability and very high in accurate capturing performance, and the accuracy of subsequent gene analysis can be greatly improved. The micro-fluidic system is easy for clinical application, is suitable for detecting metastatic malignant tumors such as prostate cancer and breast cancer in the early and middle stages, and provides technical support for precise medical detection and individualized treatment. 本发明公