Compound vitamin B and application thereof in prevention and treatment of fungal infection

• Main Authors: SONG ZHANGYONG, CHEN WENBI, XIAO WEI, ZHANG QIAN, XIN CAIYAN, LEI JUNWEN
• Format: Patent
• Language: Chinese; English
• Published: 27.11.2020
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention discloses compound vitamin B. The compound vitamin B comprises functional components vitamin B2 and vitamin B9, and the mass ratio of the vitamin B2 to the vitamin B9 is 1:(0.2-0.4). Theinvention also provides an application of the compound vitamin B in preparation of a drug for preventing and treating fungal infection. The compound vitamin B has a remarkable effect of preventing and treating the fungal infection. A compound is low in cytotoxicity, and compared with a traditional antifungal drug, the compound does not easily enable fungi to generate drug resistance, and can be used as a candidate drug of clinical antifungal infection treatment. 本发明公开了一种复合维生素B，包括功效成分维生素B2和维生素B9，所述维生素B2和维生素B9的质量比为1﹕0.2～0.4。本发明还提供该复合维生素B在制备防治真菌感染的药物中的应用。本发明的复合维生素B具有显著的防治真菌感染的作用。该复合物细胞毒性低，且与传统的抗真菌药物相比，不易使真菌产生耐药性，可作为临床抗真菌感染治疗的候选药物。