Application of cordycepin or pharmaceutically acceptable salt thereof

• Main Authors: WANG HUIJUN, LYU XING, XUE DAN, YE GUAN, WU RUOMING
• Format: Patent
• Language: Chinese; English
• Published: 06.11.2020
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention discloses an application of cordycepin or pharmaceutically acceptable salt thereof. The invention discloses an application of cordycepin or pharmaceutically acceptable salt thereof in preparation of a TYK2 inhibitor. The cordycepin can inhibit a TYK2 target of pancreatitis, cancer, psoriasis, obesity, diabetes, lupus erythematosus or inflammatory bowel disease, has prevention and/ortreatment effects on the pancreatitis, the cancer, the psoriasis, the obesity, the diabetes, the lupus erythematosus or the inflammatory bowel disease, and is safe, non-toxic and small in side effect. 本发明公开了一种虫草素或其药学上可接受的盐的应用。本发明公开了一种虫草素或其药学上可接受的盐在制备TYK2抑制剂中的应用。虫草素能够抑制胰腺炎症、癌症、银屑病、肥胖、糖尿病、红斑狼疮或炎症性肠病的TYK2靶点，对胰腺炎、癌症、银屑病、肥胖、糖尿病、红斑狼疮或炎症性肠病起到预防和/或治疗作用，同时安全无毒，副作用小。