Circular RNA marker hsa_circ_0006670 and application thereof to diagnosis of prostate cancer

• Main Author: WEI YUYAN
• Format: Patent
• Language: Chinese; English
• Published: 03.11.2020
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; ENZYMOLOGY; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPIRITS; VINEGAR; WINE

The invention relates to the field of biotechnology and biomedicine, in particular to a circular RNA marker hsa_circ_0006670 and an application thereof to diagnosis of prostate cancer. The nucleotidesequence of the marker is shown as SEQ ID No. 1. The expression of the hsa_circ_0006670 in a prostate cancer patient is increased, and whether a subject has the risk of suffering from prostate canceris judged by detecting the expression of the hsa_circ_0006670, so that the hsa_circ_0006670 can be used as an important index for clinical diagnosis and evaluation of the prostate cancer. 本发明涉及生物技术、生物医药领域，特别是一种环状RNA标志物hsa_circ_0006670，及其前列腺癌诊断中的应用，该标志物的核苷酸序列如SEQ ID No.1所示。本发明所述的hsa_circ_0006670在前列腺癌患者中表达上调，通过检测hsa_circ_0006670的表达，判断受试者是否有患前列腺癌的风险，使hsa_circ_0006670可作为前列腺癌临床诊断评估的重要指标。