Drug for treating lung cancers and preparation method thereof

• Main Authors: LUO HAILONG, YUAN XIUMEI, SUN YINGYAN, JIANG AIYING, ZHANG ZENGLEI, YUAN MEI
• Format: Patent
• Language: Chinese; English
• Published: 04.09.2020
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention belongs to the technical field of medicine, and particularly relates to a drug for treating lung cancers and a preparation method thereof. The drug contains etoposide and kaempferol, anda pharmaceutically acceptable carrier or conventional excipient. The combination of etoposide and kaempferol in a specific dosage ratio has synergistic effects on the treatment of small cell lung cancer. The combined use of the two drug active ingredients can reduce dosages of etoposide and kaempferol in the treatment of small cell lung cancer respectively, and can enhance curative effects and reduce side effects. The phenomenon can provide the scientific basis for reasonably selecting clinical drugs, reducing drug toxicity, and improving the treatment effect of small cell lung cancer. 本发明属于医药技术领域，特别涉及一种用于治疗肺癌的药物及其制备方法。该药物含有依托泊苷和山奈酚，以及药学上可接受的载体或者常规辅料。依托泊苷和山奈酚在特定用量配比下的组合对治疗小细胞肺癌具有协同作用。两种药物活性成分的联合使用，可以降低依托泊苷和山奈酚各自在治疗小细胞肺癌时的使用剂量，能够起到增强疗效和降低副作用的效果，这一现象可为合理选择临床用药，降低药物毒性，提高小细胞肺癌治疗效果提供科学依据。