Interleukin-4 receptor (IL-4R) binding protein and use thereof

• Main Authors: HAN JING, DOU CHANGLIN, DONG CHUANGCHUANG, SUN BAIPING, SONG DEYONG, CAO FAYANG
• Format: Patent
• Language: Chinese; English
• Published: 28.08.2020
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention relates to an antibody specifically binding to an IL-4R antigen, or an antigen binding fragment of the antibody, and a preparation method, composition and application of the antibody. The antibody provided by the invention has good interaction with the IL-4R antigen, can be used for preparing anti-IL-4R protein antibody drugs, and can be used for treating and/or preventing inflammations or allergies. The antibody can also be used for the immunological detection of the IL-4R antigen. 本发明涉及特异性结合IL-4R抗原的抗体或其抗原结合片段及其制备方法、组合物和应用。本发明的抗体与IL-4R抗原的相互作用良好，能够用于制备抗IL-4R蛋白抗体药物，可用于治疗和/或预防炎症或过敏症。还可用于免疫学检测IL-4R抗原。