Synthesis method of lycopene

• Main Authors: YAN RI'AN, TAN QIKUN
• Format: Patent
• Language: Chinese; English
• Published: 28.08.2020
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; METALLURGY; ORGANIC CHEMISTRY

The invention discloses a synthesis method of lycopene, which comprises the following steps: preparing 2,6,10-trimethyl-2,5,9-undecyltriene-1-aldehyde by taking pseudoionone, chloromethyl iodide, lithium bromide and trimethylsilyl lithium as raw materials; carrying out a reaction on the 2,6,10-trimethyl-2,5,9-undecyltriene-1-aldehyde with tetraethyl methylene diphosphate to obtain 3,7,11-trimethyl-1,4,6,10-tetraene dodecyl phosphonic diethyl ester; carrying out a reaction on the 3,7,11-trimethyl-1,4,6,10-tetraene dodecyl phosphonic diethyl ester with 2,7-dimethyl-2,4,6-octyltrienedialdehyde toobtain a lycopene crude product. According to the method, the problem that byproducts are difficult to separate in the existing lycopene synthesis process is solved, the intermediate in the lycopenesynthesis process is prepared by a brand-new method, the lycopene is synthesized by a three-step reaction, the synthesis process is simple, the operation is convenient, the production process is greenand environment-friendly,