PURIFICATION METHOD AND PRODUCTION METHOD OF DIFLUOROMETHYL-1, 2, 2, 2-TETRAFLUOROETHYL ETHER

• Main Authors: NISHIZAWA ERI, AKIBA SHINYA
• Format: Patent
• Language: Chinese; English
• Published: 18.08.2020
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; APPARATUS THEREFOR; CHEMISTRY; GENERAL METHODS OF ORGANIC CHEMISTRY; METALLURGY; ORGANIC CHEMISTRY

A purification method of desflurane (difluoromethyl-1, 2, 2, 2-tetrafluoroethyl ether represented by formula (1)) according to the present invention comprises a step wherein a mixture containing desflurane and a trihalomethane is brought into contact with a base in the presence of a phase transfer catalyst so as to decompose the trihalomethane. By this method, only a trihalomethane, which is a by-product contained in desflurane, is able to be decomposed without decomposing the desflurane, thereby achieving high-purity desflurane. 本发明的地氟醚(式(1)所示的二氟甲基-1,2,2,2-四氟乙醚)的精制方法包括如下工序：将包含地氟醚和三卤甲烷的混合物在相转移催化剂存在下与碱接触，使三卤甲烷分解。通过该方法，可以从包含三卤甲烷的地氟醚中，仅将作为副产物的三卤甲烷分解而地氟醚不分解，得到高纯度的地氟醚。