COMPOSITIONS AND METHODS FOR TREATMENT OF BOWEN'S DISEASE AND RELATED DISEASES

• Main Authors: OBI JUSTICE E, BASHKIN JAMES E
• Format: Patent
• Language: Chinese; English
• Published: 17.07.2020
• Subjects: AGRICULTURE; ANIMAL HUSBANDRY; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES; FISHING; FORESTRY; HUMAN NECESSITIES; HUNTING; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF; TRAPPING

Compositions and methods for the treatment of Bowen's disease, an orphan disease, are described. In addition, compositions and methods for the treatment of recurrent respiratory papillomatosis (RRP),an orphan disease, are described. Compositions and methods for the treatment of stage 1 melanoma are also described. The compositions comprise one or more active ingredients selected from the group consisting of: chloroquine, amodiaquine, and an antibiotic such as metronidazole. The methods comprise administering a therapeutically effective amount of such compositions to a subject in need thereof. 描述了治疗一种罕见疾病鲍恩病的组合物和方法。此外，描述了用于治疗一种罕见疾病复发性呼吸道乳头状瘤病(RRP)的组合物和方法。还描述了用于治疗1期黑素瘤的组合物和方法。所述组合物包含一种或多种活性成分，其选自氯喹、阿莫地喹和抗生素，例如甲硝唑。所述方法包括对有此需要的受试者施用治疗有效量的这类组合物。