Regulatory macrophages for treating angiopathies

• Main Author: FANDRICH FRED
• Format: Patent
• Language: Chinese; English
• Published: 14.07.2020
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

The present invention relates to the use of immunoregulatory macrophages for treating diseases that are associated with pathological changes of the blood vessels. The present invention particularly relates to the use of immunoregulatory macrophages for treating micro-and macroangiopathies of the lower limbs. The invention furthermore relates to the use of immunoregulatory macrophages for promotingtissue remodelling to facilitate wound healing.Pharmaceutical compositions for use in the recited treatments are also disclosed which comprise the immunoregulatory macrophages. 本发明涉及免疫调节性巨噬细胞用于治疗疾病的用途，所述疾病与血管的病理学变化有关。本发明具体地涉及免疫调节性巨噬细胞用于治疗下肢的微血管病和大血管病的用途。此外，本发明涉及免疫调节性巨噬细胞用于促进组织重塑以推进伤口愈合的用途。还公开了用于用在所述治疗中的药物组合物，其包含免疫调节性巨噬细胞。