Compounds and use thereof in the expansion of stem cells and/or progenitor cells

• Main Authors: YEH JONATHAN, MARINIER ANNE, CHANTIGNY YVES, SIMONEAU BRUNO, SAUVAGEAU GUY
• Format: Patent
• Language: Chinese; English
• Published: 14.07.2020
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

The invention relates to compounds of formula I and pharmaceutical compositions containing them. Also, the invention relates to methods for expanding stem cells and/or progenitor cells and methods fortreating a hematopoietic disorder/malignancy, and autoimmune disease and/or an inherited immunodeficient disease (I). 本发明涉及式I的化合物和含有所述化合物的药物组合物。另外，本发明涉及扩增干细胞和/或祖细胞的方法以及治疗造血障碍/恶性肿瘤、自体免疫疾病和/或遗传性免疫缺陷疾病的方法。