COUMARIN DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND USES THEREOF FOR TREATMENT OF CANCER

• Main Authors: CHOIDAS AXEL, GUSTAFSSON CLAES M, KOCH UWE, UNGER ANKE, FALKENBERG-GUSTAFSSON MARIA, DI LUCREZIA RAFFAELLA, NUSSBAUMER PETER, LARSSON NILS-G RAN, BERGBREDE TIM, KLEBL BERT
• Format: Patent
• Language: Chinese; English
• Published: 07.07.2020
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention provides novel coumarin derivatives as specific mitochondrial RNA polymerase inhibitors for the treatment of cancer. 本发明提供了作为用于治疗癌症的特异性线粒体RNA聚合酶抑制剂的新香豆素衍生物。