Preparation method of 3, 4-dimethoxybenzonitrile

• Main Authors: SHEN ZHENPENG, ZHAO ZHE, LIU WENBO, TIAN XINZHE, REN YUNLAI
• Format: Patent
• Language: Chinese; English
• Published: 19.06.2020
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; METALLURGY; ORGANIC CHEMISTRY

The invention provides a preparation method of 3, 4-dimethoxybenzonitrile, which comprises the following steps of adding 3, 4-dimethoxyphenyl acetone and nitrogen oxide into an organic solvent, and carrying out catalytic reaction by an iron catalyst under the protection of inert gas to obtain the 3, 4-dimethoxybenzonitrile. According to the method, 3, 4-dimethoxyphenyl acetone is used as a raw material, so that high yield can be realized at a relatively mild reaction temperature. 本发明提供一种3,4-二甲氧基苯甲腈的制备方法：将3,4-二甲氧基苯基丙酮和氮氧化物加入有机溶剂中，在惰性气体保护下，由铁类催化剂催化反应得到3,4-二甲氧基苯甲腈。该方法以3,4-二甲氧基苯基丙酮为原料，能够在较为温和的反应温度下实现不错的收率。