Polymyxin analogue and preparation method therefor

• Main Authors: XU HONGJINAG, ZHANG XIQUAN, ZHANG YOU, FENG JUN, LU JIANGUANG, TANG HANQING, DONG YUANZHEN
• Format: Patent
• Language: Chinese; English
• Published: 05.06.2020
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention belongs to the field of medicines, and relates to a polymyxin analogue having high antibacterial activity, and a preparation method therefor and an application thereof. The polymyxin analogue has a broad-spectrum and high-efficiency bactericidal effect on drug-resistant bacteria and fungi. 本发明属于医药领域，涉及具有高抗菌活性的多黏菌素类似物及其制备方法与应用，本发明的多黏菌素类似物对耐药细菌、真菌具有广谱、高效的杀菌效果。