Method for selectively reducing carbon-carbon double bonds in alpha, beta-unsaturated carbonyl compound

• Main Authors: QIN YONGWEI, LU JINGJUN, ZOU ZIRONG, LI YAMEI, HUANG YUBING, HONG HUANLIANG
• Format: Patent
• Language: Chinese; English
• Published: 02.06.2020
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; HETEROCYCLIC COMPOUNDS; METALLURGY; ORGANIC CHEMISTRY

The invention discloses a method for selectively reducing carbon-carbon double bonds in an alpha, beta-unsaturated carbonyl compound. The method comprises the following steps: in an electrolysis system, adding the alpha, beta-unsaturated carbonyl compound represented by formula (I), and reducing the carbon-carbon double bonds conjugated with carbonyl in the alpha, beta-unsaturated carbonyl compound through an electrochemical cathode reduction reaction. Compared with reported methods, the method has the following advantages: metal catalysts and external oxidants are not used, and reaction raw materials and an electrolyte used in the method are low in price, nontoxic, odorless and simple and convenient in post-treatment, so that the method is suitable for industrial production, mild in reaction conditions, simple to operate and high in yield, and is an efficient and practical synthetic method of ester and amide compounds. 本发明公开了一种选择性还原α,β-不饱和羰基化合物中碳碳双键的方法，包括以下步骤：在电解体系中，加入式(I)所示的α，β-不饱和羰基化合物，通过电化学阴极还原反应将α，β-不饱和羰