SKIN EXTERNAL PREPARATION COMPOSITION FOR MOISTURIZING SKIN CONTAINING 1,2,3,4,6-PENTA-O-GALLOYL-beta-D-GLUCOSE

• Main Authors: KIM KYU HAN, SHIM JIN SUP, LEE TAE RYONG, SON EUI DONG
• Format: Patent
• Language: Chinese; English
• Published: 12.05.2020
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS

The present invention relates to skin external preparation composition containing 1,2,3,4,6-penta-O-galloyl-beta-D-glucose (hereinafter referred to as "PGG"), and more particularly, to a skin externalpreparation composition, a use thereof, and a method for moisturizing the skin using same, wherein the skin external preparation composition, due to containing PGG, stimulates the formation of filaggrin in keratinocytes, increases loricrin and involucrin expression, thereby stimulating the formation of a normal keratin layer, and as a result, can strengthen the skin barrier function to provide anexcellent skin moisturization improving effect. 本发明涉及一种含有1,2,3,4,6-五-O-没食子酰基-β-D-葡萄糖(以下，称为"PGG")的皮肤外用剂组合物，更加详细而言，涉及通过含有PGG，在角质形成细胞中促进丝聚蛋白的生成，增加兜甲蛋白(loricrin)以及外皮蛋白(involucrin)的表达，促进正常的角质层的形成，由此强化皮肤屏障功能，从而能够提供改善皮肤保湿力的效果的皮肤外用剂组合物、其用途以及利用其的皮肤保湿方法。