Anti-L1-CAM antibodies and uses thereof

The present disclosure relates generally to immunoglobulin-related compositions (e.g., antibodies or antigen binding fragments thereof) that can bind to and neutralize the activity of L1-CAM protein.The antibodies of the present technology are useful in methods for detecting and treating a L1-CAM-po...

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Bibliographic Details
Main Authors NEMIEBOKA BRANDON, XU HONG, CHEUNG NAI-KONG, LEWIS JASON, SUZUKI-NISHIJIMA MAYA
Format Patent
LanguageChinese
English
Published 01.05.2020
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present disclosure relates generally to immunoglobulin-related compositions (e.g., antibodies or antigen binding fragments thereof) that can bind to and neutralize the activity of L1-CAM protein.The antibodies of the present technology are useful in methods for detecting and treating a L1-CAM-positive cancer in a subject in need thereof. 本申请总体上涉及可以与L1-CAM蛋白结合并中和其活性的免疫球蛋白相关组合物(例如，抗体或其抗原结合片段)。本申请的抗体可用于检测和治疗有需要的受试者中L1-CAM阳性癌症的方法。
Bibliography:Application Number: CN201880052266