Method for protecting liver from alcoholic injury through oral administration of melatonin

• Main Authors: GUAN SHENGYU, LIU GUOSHI, LYU DONGYING, YAO YUJUN, ZHU TIANQI, ZHANG LU, JI PENGYUN
• Format: Patent
• Language: Chinese; English
• Published: 03.04.2020
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention provides a method for relieving alcohol injury to the liver of an animal through oral administration of melatonin. According to the method, the melatonin is directly added into the alcohol, so that the toxic action after the intake of the alcohol by animals is relieved to achieve the goal of relieving the liver injury after intake of the alcohol. The method provided by the inventionhas the advantages that the toxic action of the alcohol on the liver and the reproductive organ of a mouse can be obviously relieved; the weight increase speed of the mouse is obviously accelerated; and the body weight of the mouse is obviously increased. Therefore, the method provided by the invention is favorable for relieving the toxic action of the alcohol on the liver and the reproductive organ of the mouse without bringing adverse influence to the mouse, so that the goal of maintaining the body health is achieved. 本发明提供了一种通过口服褪黑素来改善酒精对动物肝脏损伤的方法，所述方法通过在酒精中直接添加褪黑素，从而改善动物在摄入酒精后的毒害作用，以达到改善摄入酒精后对肝的损伤的目的。本发明所述方法能够显著改善