CARBON MONOXIDE RELEASING NORBORNENONE COMPOUNDS

• Main Authors: STANLEY NATHAN JOHN, GILES GREGORY, KUEH JUI THIANG BRIAN, JAY-SMITH MORGAN, LARSEN DAVID SAMUEL, SMITH ROBIN ANDREW JAMES, LARSEN LESLEY, WOODS LAURA MOLLY, BRIMBLE MARGARET ANNE, SAMMUT IVAN ANDREW, HEWITT RUSSELL JAMES, READ MORGAYN IONA, RENNISON DAVID, HARRISON JOANNE CLARE
• Format: Patent
• Language: Chinese; English
• Published: 24.03.2020
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; DERIVATIVES THEREOF; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; NUCLEIC ACIDS; NUCLEOSIDES; NUCLEOTIDES; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SUGARS

The present invention provides organic compounds which are capable of releasing carbon monoxide under physiological conditions or pH trigger, and to the use of such compounds for conditioning a cell,tissue or organ, for example, to protect against ischaemic injury during a transplant event. 本发明提供了有机化合物，其能够在生理条件下或pH触发剂作用下释放一氧化碳，并涉及所述化合物调理细胞、组织或器官的用途，例如，以在移植事件期间保护避免发生缺血性损伤。