Application of chimonanthine to nasopharyngeal carcinoma resisting

• Main Authors: ZHU YANGCHEN, ZHAO LING
• Format: Patent
• Language: Chinese; English
• Published: 28.02.2020
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention discloses application of chimonanthine to nasopharyngeal carcinoma resisting. According to an embodiment, on the one hand, the chimonanthine is capable of effectively inhibiting proliferation of human nasopharyngeal carcinoma CNE2 cells to hinder growth of human nasopharyngeal carcinoma, and on the other hand, the chimonanthine is capable of effectively inhibiting migration of the human nasopharyngeal carcinoma CNE2 cells to hinder metastasis and invasion of human nasopharyngeal carcinoma. On the basis of activity of the chimonanthine on the human nasopharyngeal carcinoma CNE2 cells, the chimonanthine can be used for preparation of nasopharyngeal carcinoma resisting medicines for treatment of nasopharyngeal carcinoma. 本发明公开了一种素心腊梅碱的抗鼻咽癌用途。本发明实施例表明，素心腊梅碱一方面可以有效抑制人鼻咽癌CNE2细胞的增殖，阻碍人鼻咽癌的生长；另一方面可以有效抑制人鼻咽癌CNE2细胞的迁移，阻碍人鼻咽癌的转移和侵袭。基于素心腊梅碱对人鼻咽癌CNE2细胞上述两方面的活性，其可以用于制备成抗鼻咽癌的药物用于鼻咽癌的治疗。