COMPOSITIONS AND METHODS COMPRISING A TRIARYL POLYAMINE

• Main Authors: WILLIAMS DUSTIN, HAUSSENER TRAVIS J, REDDY HARIPRASADA R KANNA, LOOPER RYAN E, SEBAHAR PAUL R
• Format: Patent
• Language: Chinese; English
• Published: 11.02.2020
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; AGRICULTURE; ANIMAL HUSBANDRY; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES; CHEMISTRY; FISHING; FORESTRY; HUMAN NECESSITIES; HUNTING; METALLURGY; ORGANIC CHEMISTRY; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF; TRAPPING

Compounds, compositions, and methods comprising a polyamine compound are described, which may be used to kill, disperse, treat, or reduce biofilms, or to inhibit or substantially prevent biofilm formation. In some aspects, the present invention relates to polyamine compounds that have antimicrobial or dispersing activity against a variety of bacterial strains capable of forming biofilms. In some aspects, the present invention relates to compositions and methods comprising the polyamine compound. In some aspects, the compounds, compositions, and methods enhance wound healing. 描述了包含聚胺化合物的化合物、组合物和方法，其可以用于杀灭、分散、处理或减少生物膜或抑制或基本上防止生物膜形成。在一些方面，本发明涉及具有针对能够形成生物膜的各种菌株的抗微生物或分散活性的聚胺化合物。在一些方面，本发明涉及包含聚胺化合物的组合物和方法。在一些方面，所述化合物、组合物和方法促进伤口愈合。