Adamantyl trimethyl ammonium hydroxide preparation method

• Main Authors: DONG ZHUYONG, WU QINMING, LI QINGSHAN, SHEN YONGMIAO, WANG XINWEI, WU JIANPING, WANG DANYAN, SHI XUSHENG
• Format: Patent
• Language: Chinese; English
• Published: 17.01.2020
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; APPARATUS THEREFOR; CHEMISTRY; ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTIONOF COMPOUNDS OR NON-METALS; METALLURGY; ORGANIC CHEMISTRY

The invention discloses an adamantyl trimethyl ammonium hydroxide preparation method, and belongs to the technical field of chemical synthesis. The method comprises: (1) carrying out a reaction for acertain time in an organic solvent by using 1-bromoadamantane as a starting raw material, using a dimethylamine salt as an amination reagent and using triethylamine as a dimethylamine release agent toobtain N,N-dimethyladamantadine; and (2) preparing adamantyl trimethyl ammonium hydroxide from the N,N-dimethyladamantane amine, wherein the N,N-dimethyladamantadine reacts with chloromethane to obtain adamantyl trimethyl ammonium chloride, and then the adamantyl trimethyl ammonium chloride is electrolyzed to obtain the adamantyl trimethyl ammonium hydroxide. The method of the invention has advantages of safety, environmental protection, high yield and the like. 本发明公开了一种金刚烷基三甲基氢氧化铵的制备方法，属于化学合成技术领域，其特征在于，包括以下步骤：（1）、以1-溴金刚烷为起始原料，二甲胺盐为胺化试剂，三乙胺为二甲胺的释放剂，在有机溶剂中进行一定时间的反应，得到N,N-二甲基金刚烷胺；（2）、N,N-二甲基金刚烷胺制备金刚烷基三甲基氢氧化铵：N,N-二甲基金刚烷胺