Protein retrieval model construction method, retrieval method and device and storage medium

• Main Authors: ZHANG GUANGPING, LUO YUANSHENG, PENG YUXU, PENG XIAN, HUANG YUANYUAN
• Format: Patent
• Language: Chinese; English
• Published: 10.12.2019
• Subjects: INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS; PHYSICS

The invention discloses a protein retrieval model construction method, a protein retrieval method and device, and a storage medium. The method comprises the steps: at respectively generating triangular grids of which the surfaces are excluded by solvents for all proteins in a data set, and carrying out redundancy removal and noise removal simplification processing on the triangular grids, therebyshortening the retrieval time and improving the retrieval efficiency. According to a retrieval algorithm, the WKS algorithm and the HKS algorithm are integrated, so the invariance of the shape descriptor in the conversion process is kept, the insensitivity of the shape descriptor to protein deformation is enhanced, and the retrieval precision is improved. 本申请公开了一种蛋白质检索模型构建方法、检索方法、设备和存储介质，对数据集中的所有蛋白质分别生成溶剂排除表面的三角网格，对三角网格进行去冗余和去噪声的简化处理，缩短检索时间，提高检索效率；检索算法融合WKS与HKS两种算法，保持了形状描述符在转换过程中的不变性，加强了形状描述符对蛋白质变形的不敏感性，提高了检索精度。