Compositions comprising a fatty acid oil mixture and a surfactant, and methods and uses thereof

• Main Authors: OLESEN PREBEN HOULBERG, KLAVENESS JO ERIK JOHNSRUD, BERGE GUNNAR, HUSTVEDT SVEIN OLAF
• Format: Patent
• Language: Chinese; English
• Published: 06.12.2019
• Subjects: FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

A pre-concentrate comprises a fatty acid oil mixture that contains EPA and DHA, preferably in the form of ethyl ester or triglyceride, and at least one surfactant. The pre-concentrates are capable offorming a self-nano-emulsifying drug delivery system, a self-micro-emulsifying drug delivery system or a self-emulsifying drug delivery system (SNEDDS, SMEDDS or SEDDS) in an aqueous solution. The application is also directed to a food supplement pre-concentrate. 本发明涉及医药预浓缩物，其含有：含EPA和DHA的脂肪酸油混合物，所述EPA和DHA优选形式为乙酸或甘油三酯；以及至少一种表面活性剂。所述预浓缩物能够在水溶液中形成自纳米乳化药物递送系统、自微乳化药物递送系统或自乳化药物递送系统(SNEDDS、SMEDDS或SEDDS)。本申请还涉及食品补充剂预浓缩物。