糖皮质激素受体调节剂治疗宫颈癌

公开了治疗患有癌性肿瘤的对象的方法。该方法包括给予对象有效量的非类固醇选择性糖皮质激素受体调节剂(SGRM)和有效量的化学治疗剂。肿瘤可能是宫颈癌。SGRM可以是稠合的氮杂萘烷。在实施方案中，SGRM可以是杂芳基酮稠合的氮杂萘烷或八氢稠合的氮杂萘烷。 Methods for treating a subject having a cancerous tumor are disclosed. The methods comprise administering to the subject an effective amount of a non-steroidal selective gluc...

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Bibliographic Details
Format Patent
LanguageChinese
Published 04.07.2023
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:公开了治疗患有癌性肿瘤的对象的方法。该方法包括给予对象有效量的非类固醇选择性糖皮质激素受体调节剂(SGRM)和有效量的化学治疗剂。肿瘤可能是宫颈癌。SGRM可以是稠合的氮杂萘烷。在实施方案中，SGRM可以是杂芳基酮稠合的氮杂萘烷或八氢稠合的氮杂萘烷。 Methods for treating a subject having a cancerous tumor are disclosed. The methods comprise administering to the subject an effective amount of a non-steroidal selective glucocorticoid receptor modulator (SGRM) and an effective amount of a chemotherapeutic agent. The tumor may be cervical cancer. The SGRM may be a fused azadecalin. In embodiments, the SGRM may be a heteroaryl ketone fused azadecalin or an octahydro fused azadecalin.
Bibliography:Application Number: CN20188023127