PROCESS FOR PREPARING METHYL PHOSPHINIC ACID BUTYL ESTER

• Main Authors: KALINOVICH NATALIYA, ERCHOV LEONID, SHTERENBERG ALEXANDER, SHEVCHUK MYKHAILO, FRONTON SVETA, YACOVAN AVIHAI, ROESCHENTHALER GERD-VOLKER, STUBBMANN-KAZAKOVA OLESYA
• Format: Patent
• Language: Chinese; English
• Published: 22.11.2019
• Subjects: ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM; CHEMISTRY; METALLURGY; ORGANIC CHEMISTRY

The present subject matter provides a safe alternative for producing an important intermediate useful for preparing the herbicide glufosinate, without need for chlorine components in the manufacturingprocess. In particular, a process for preparing alkyl phosphinic aid alkyl ester is provided, including the step of alkylating alkyl phosphinic acid ester in a non-polar solvent in the same apparatusas used to first produce the alkyl phosphinic acid ester, and without isolating the alkyl phosphinic acid ester before the alkylation step is conducted. More specifically, a process is presented forpreparing methyl phosphinic acid butyl ester, by alkylating butyl phosphinic acid ester in a non-polar solvent, in the same' apparatus as used previously to first produce the butyl phosphinic acid ester and without isolating the butylphosphinic acid ester before alkylation. 本主题提供了一种用于生产可用于制备除草剂草铵膦的重要中间体的安全替代品，在生产过程中不需要氯成分。特别是，提供了一种制备烷基次膦酸烷基酯的方法，包括在与用于首次生产烷基次膦酸酯相同的设备中，在非极性溶剂中使烷基次膦酸酯烷基化的步骤，并在执行烷基化步骤之前不分离烷基次膦酸酯。更具体地说，提出了在与之前用于