PUM 1 protein as target for virus inhibition

• Main Authors: LIU YONGHONG, ZHOU GRACE, ROIZMAN BERNARD
• Format: Patent
• Language: Chinese; English
• Published: 15.11.2019
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

Disclosed is a method for prophylaxis or treatment of infection of a virus, or for modulating innate immunity, in a subject comprising administering to the subject a therapeutically effective amount of a PUM1 inhibitor. A pharmaceutical composition comprising the PUM1 inhibitor is also disclosed. 公开了一种在对象中用于预防或治疗病毒感染或用于调节先天免疫的方法，包含向所述对象施用治疗有效量的PUM1抑制剂。还公开了包含所述PUM1抑制剂的药物组合物。