COMPOUND HAVING BRUTON'S TYROSINE KINASE (BTK)-INHIBITION AND DEGRADATION ACTIVITY

A compound having Bruton's tyrosine kinase (Btk)-inhibition and degradation activity as represented by formula I. The compound has excellent Btk-inhibition activity and can degrade Btk, and can be used for preparing drugs for treatment of Btk activity-related diseases. (I). 一类具有抑制并降解布鲁顿酪氨酸蛋白激酶B...

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Bibliographic Details
Main Author SHU YONGZHI
Format Patent
LanguageChinese
English
Published 15.11.2019
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A compound having Bruton's tyrosine kinase (Btk)-inhibition and degradation activity as represented by formula I. The compound has excellent Btk-inhibition activity and can degrade Btk, and can be used for preparing drugs for treatment of Btk activity-related diseases. (I). 一类具有抑制并降解布鲁顿酪氨酸蛋白激酶Btk活性的式I化合物，其具有很好的Btk抑制活性并能将Btk降解，可以用于制备治疗间Btk活性相关的疾病的药物。(I)
Bibliography:Application Number: CN201880004080