Microfluidic chip and application thereof in particle cleaning and liquid replacement

• Main Authors: GUO XIAOLIANG, MA ZHOUYANG
• Format: Patent
• Language: Chinese; English
• Published: 08.11.2019
• Subjects: CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE; CLEANING; CLEANING IN GENERAL; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; PERFORMING OPERATIONS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; PHYSICS; PREVENTION OF FOULING IN GENERAL; TESTING; TRANSPORTING

The invention provides a microfluidic chip and an application thereof in particle cleaning and liquid replacement. The micro-fluidic chip comprises a chip body; the chip body is a sealed cuboid cavity-type structure; each of the left side surface and the right side surface of the chip body is provided with an upper port and a lower port which are used for connecting the inside of a chip cavity with the outside; N rows of micro-columns are uniformly arranged in the chip body cavity to form an array structure, wherein N is an integer more than or equal to 2; and the top surface and the bottom surface of each micro column are respectively and tightly connected with an upper substrate and a lower substrate of the chip body. The arrangement mode of the array structure is as follows: the micro columns in the (N+1)th row are obliquely arranged relative to the micro columns in the Nth row, and the inclined angle is smaller than 60 degrees. The cavity between every two adjacent micro-columns isa channel for liquid flo