Bladder cancer diagnosis system and method of detecting methylation level of target gene in urine

• Main Author: HAN JUN
• Format: Patent
• Language: Chinese; English
• Published: 25.10.2019
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; COMPOSITIONS THEREOF; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; CULTURE MEDIA; ENZYMOLOGY; HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATIONTECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING ORPROCESSING OF MEDICAL OR HEALTHCARE DATA; INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PHYSICS; PROCESSES OF PREPARING SUCH COMPOSITIONS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

The invention discloses a method of noninvasively detecting bladder cancer. The method can provide early screening of bladder cancer, estimate the risk of a subject to experience bladder cancer, and provide typing of bladder cancer and/or prognostic prediction, so that diagnostic sensitivity, specificity and accuracy are improved; noninvasive, convenient, efficient and rapid diagnosis of bladder cancer is achieved. The invention also provides a bladder cancer diagnosis system, as well as a method of detecting methylation level of a target gene in urine. 本发明公开了一种膀胱癌的无创检测方法。本发明的膀胱癌的无创检测方法可以实现膀胱癌的早期筛查、受试者发生膀胱癌的风险评估、膀胱癌的分型和/或预后预测，提高了诊断的灵敏度、特异性和准确性，实现了无创、便捷、高效、快速诊断膀胱癌的效果。本发明还提供了一种膀胱癌诊断系统。本发明还提供了一种检测尿液中目的基因甲基化水平的方法。