USE OF A SIRNA FOR TREATING CANCER

• Main Authors: BROOKS HILARY, CHUSSEAU MAUD, CABON FLORENCE, DELMAS STEPHANIE
• Format: Patent
• Language: Chinese; English
• Published: 18.10.2019
• Subjects: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

The present invention concerns a composition comprising at least one siRNA, said siRNA hybridising with a coding or non-coding mRNA, in which it induces degradation or inhibits translation, the expression of said mRNA or of the protein for which it codes being implicated in a pathology, for the use of same in the prevention and/or the treatment of said pathology, said composition being formulatedfor a continuous systemic administration mode, and a device comprising such an administration mode. 本发明涉及一种至少包括一种siRNA的组合物，所述siRNA与编码或非编码mRNA杂交以诱导所述mRNA降解或抑制所述mRNA的翻译，所述mRNA或其编码蛋白的表达参与疾病，所述组合物用于预防和/或治疗所述疾病，所述组合物被配制用于连续的全身给药模式,本发明还涉及包含这样给药模式的装置。