POST-TRANSCRIPTIONALLY CHEMICALLY MODIFIED DOUBLE STRAND RNAS

Described are post transcriptionally chemically modified double strand RNAs (MdsRNAs) having more than 30 base pairs. The MdsRNAs inhibit gene expression in target organisms. Also described are methods of making and using MdsRNAs. 描述了具有多于30个碱基对的转录后化学修饰的双链RNA(MdsRNA)。这些MdsRNA抑制靶生物中的基因表达。还描述了制备和使用MdsR...

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Bibliographic Details
Main Authors ARHANCET JUAN P, ROZEMA DAVID B, CHEERLA SREEVISHNU, ARHANCET GRACIELA B
Format Patent
LanguageChinese
English
Published 11.10.2019
Subjects
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
BEER
BIOCHEMISTRY
CHEMISTRY
DERIVATIVES THEREOF
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SPIRITS
SUGARS
VINEGAR
WINE
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Summary:Described are post transcriptionally chemically modified double strand RNAs (MdsRNAs) having more than 30 base pairs. The MdsRNAs inhibit gene expression in target organisms. Also described are methods of making and using MdsRNAs. 描述了具有多于30个碱基对的转录后化学修饰的双链RNA(MdsRNA)。这些MdsRNA抑制靶生物中的基因表达。还描述了制备和使用MdsRNA的方法。
Bibliography:Application Number: CN201780082503