METHODS OF MAKING SUBSTITUTED PORPHYRIN PHARMACEUTICAL COMPOUNDS AND COMPOSITIONS

Described herein are methods and intermediates useful for making substituted porphyrins, including Mn(III) ortho N-butoxyethylpyridylporphyrin, and compositions comprising the same. In some embodiments, a method of the present invention provides a composition having a certain percentage or yield (e....

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Main Authors BATINIC-HABERLE INES, TOVMASYAN ARTAK, LEE CHRISTOPHER ALLEN, SPASOJEVIC IVAN, DZOLIC ZRINKA RAJIC
Format Patent
LanguageChinese
English
Published 27.09.2019
Subjects
APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Described herein are methods and intermediates useful for making substituted porphyrins, including Mn(III) ortho N-butoxyethylpyridylporphyrin, and compositions comprising the same. In some embodiments, a method of the present invention provides a composition having a certain percentage or yield (e.g., at least 80%, 85%, 90%, or 95% by weight) of a compound of the present invention. 本文记载了用于制备取代卟啉，包括Mn(III)邻位丁氧基乙基吡啶基卟啉的方法和中间体，以及包含所述取代卟啉，包括Mn(III)邻位丁氧基乙基吡啶基卟啉的组合物。在一些实施方案中，本发明的方法提供了一种具有特定百分比或产率（例如，至少80重量％、85重量％、90重量％或95重量％）的本发明化合物的组合物。
Bibliography:Application Number: CN201780086851