Targeted detection for XY disorders of sex development

• Main Authors: WANG NAN, ZHU WENJIAO, CHENG TONG, ZHU HUI, ZHAO SHUANGXIA, HAN BING, WANG HAO, SONG HUAIDONG, QIAO JIE
• Format: Patent
• Language: Chinese; English
• Published: 24.09.2019
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; COMPOSITIONS THEREOF; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; CULTURE MEDIA; ENZYMOLOGY; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PROCESSES OF PREPARING SUCH COMPOSITIONS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

The invention provides targeted detection for XY disorders of sex development, in particular to use of genes associated with disorders of sex development or loci of the genes, and/or detection reagents for the genes or the loci, for preparing a reagent or a kit, wherein the reagent or the kit is used for detecting the susceptibility of a subject to the disorders of sex development, and the genes associated with the disorders of sex development are selected from the group consisting of SRD5A2, AR and NR5A1. 本发明提供了一种针对XY性发育异常疾病的靶向检测，具体地，本发明提供性发育异常相关基因或其位点、和/或其检测试剂的用途，用于制备试剂或试剂盒，所述试剂或试剂盒用于检测被检测对象对性发育异常的易感性，所述性发育异常相关基因选自下组：SRD5A2、AR和NR5A1。