COSMETIC COMPOSITIONS CONTAINING QUINONES AND THEIR TOPICAL USE ON SKIN AND HAIR

• Main Authors: BOICE MICHAEL, BORCHETTA FRANK, TRENT JOHN, YANG CHENYI, CUNNINGHAM ALBERT, ZHOU PENGBO
• Format: Patent
• Language: Chinese; English
• Published: 03.09.2019
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS

Described are compositions containing quinones that show activity in enhance DNA repair and/or prevent damage to DNA. The quinones are thymoquinone, lapachol, myrtucommulone C, or mixtures thereof, and can be formulated into cosmetic compositions for topical administration to a subject in need thereof. The cosmetic compositions can also include sunscreens, surfactants, sunless tanning agents, desquamation agents, antiperspirants, colorants, preservatives and mixtures; and a cosmetically acceptable carrier. The compositions should find use in methods for treating the signs of ageing in mammalsvia topical application to the skin or hair of the mammals. 描述了含有醌的组合物，其显示出在增强DNA修复和/或防止对DNA的损伤方面的活性。所述醌是百里醌、拉帕醇、myrtucommulone C或其混合物，并且可以配制成用于局部施用至需要其的受试者的化妆品组合物。化妆品组合物还可以包括遮光剂、表面活性剂、无日光鞣剂、脱屑剂、止汗剂、着色剂、防腐剂和混合物；以及化妆品可接受的载体。所述组合物应可用于经由局部施用至哺乳动物的皮肤或毛发来治疗哺乳动物的衰老迹象的方法。