HETROARYLAMINE COMPOUNDS FOR MODULATING THE HEDGEHOG PATHWAY AND PREPARING METHOD AND USES THEREOF

The present invention provides a compound of formula (I) wherein X, Y, Z1, Z2, R1, R2, A, B, p and q are as disclosed in the specification. A pharmaceutical composition and a method for modulating theHedgehog pathway are also provided. The present invention further provides a process for preparing t...

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Bibliographic Details
Main Authors LU YANN-YU, KUO MANN-YAN, YANG JU-YING, LIU CHIA-WEI, HSIEH SELINE, LEE YING-SHUAN
Format Patent
LanguageChinese
English
Published 16.08.2019
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides a compound of formula (I) wherein X, Y, Z1, Z2, R1, R2, A, B, p and q are as disclosed in the specification. A pharmaceutical composition and a method for modulating theHedgehog pathway are also provided. The present invention further provides a process for preparing the compound. 本发明提供一种式(I)的化合物：其中X、Y、Z、Z、R、R、A、B、p和q如说明书中所公开。还提供一种用于调节刺猬途径的医药组合物和方法。本发明另提供一种用于制备所述化合物的方法。
Bibliography:Application Number: CN201780072354