Radioactivity-related disease diagnosis marker and application thereof

• Main Authors: YU WEISONG, SONG XUESHU
• Format: Patent
• Language: Chinese; English
• Published: 02.08.2019
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

The invention discloses a radioactivity-related disease diagnosis marker and application thereof. Through high-throughput sequencing combined with bioinformatics and large sample verification, the phenomenon that LINC01485 remarkably decreases in breast cancer is firstly found. As a novel biological marker, LINC1485 has relatively high specificity and sensitivity. 本发明公开了一种放射性相关疾病诊疗标志物及其应用，本发明通过高通量测序技术结合生物信息学分析以及大样本验证，首次发现了LINC01485在乳腺癌中显著下调。LINC01485作为新型的生物标志物，具有较高的特异性和灵敏性。