Composition and method for adjusting HBV and TTR expression

The invention provides a composition and method for adjusting HBV and TTR expression. Provided herein are oligomeric compounds with conjugate groups. In certain embodiments, the oligomeric compounds are conjugated to N-Acetylgalactosamine. 本文提供了用于调节HBV和TTR表达的组合物和方法。本文还提供了具有缀合物基团的低聚化合物。在某些实施方案中，所述低聚化...

Full description

Saved in:
Bibliographic Details
Main Authors SETH PUNIT P, PRAKASH THAZHA P, SWAYZE ERIC E
Format Patent
LanguageChinese
English
Published 23.07.2019
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
Online AccessGet full text

Cover

More Information
Summary:The invention provides a composition and method for adjusting HBV and TTR expression. Provided herein are oligomeric compounds with conjugate groups. In certain embodiments, the oligomeric compounds are conjugated to N-Acetylgalactosamine. 本文提供了用于调节HBV和TTR表达的组合物和方法。本文还提供了具有缀合物基团的低聚化合物。在某些实施方案中，所述低聚化合物缀合至N-乙酰基半乳糖胺。
Bibliography:Application Number: CN201910036892